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PART D: SCIENCE BASE

Figure D4-2. IOM Figure 8-3: Calculated Changes in Serum LDL Cholesterol Concentration in Response to Percent Change Dietary Saturated Fatty Acids

This graph includes three regression equations that were used to calculate changes in LDL cholesterol in response to changes in dietary saturated fatty acids. Saturated fatty acid intake ranged from 2.2 to 33 percent of energy. For all three regression equations and the mean, the change in LDL cholesterol increased as saturated fatty acid intake increased, ranging from 0.033 mmol/L to 0.045 mmol/L.

Three regression equations were used to establish the response curves. The range in saturated fatty acid intake was 2.2 to 33 percent of energy.

Source: IOM (Institutes of Medicine). Dietary Reference Intakes: Energy, Carbohydrates, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: National Academies Press, 2002.

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